Choose the Power of Liquid Nitrogen Cryoablation

Uniquely powered by liquid nitrogen, the ProSense™ cryoablation system generates ultra-cold temperatures quickly to create large lethal zones for maximum tumor destruction. 

Technology

Choose the Power of Liquid Nitrogen Cryoablation

Uniquely powered by liquid nitrogen, the ProSense™ cryoablation system generates ultra-cold temperatures quickly to create large lethal zones for maximum tumor destruction. 

Choose Maximum Tumor Destruction

Large lethal zones

Low temperatures
-160°C ± 10°C

Effective freeze

Effective freeze

Rapid temperature drop

Temperatures

Large ice ball

Slow passive thaw between
freezing cycles

Easy-to-use

Single cryoprobe, intuitive user interface and relocation options

The ProSense single cryoprobe system is as effective at creating a large lethal zone as three cryoprobes from an argon based multiprobe system. 

IceCure LN2 Technology Graph

*Data source: Other LN2 system – Internal IceCure testing of competitor device in 2021;
Argon system – data from competitor product brochure.

Choose Superior Cooling with Liquid Nitrogen Cryoablation   

Powered by liquid nitrogen, the coldest cryogen which boils at -196°C*, the ProSense Cryoablation System successfully addresses the three core principles required for an effective and efficient cryoablation:
  • Rapid temperature drop can reach below -160°C ± 10°C to create large lethal zones
  • Temperatures stay consistently stable and low to enable effective freeze cycles
  • Slow passive thaw between freezing cycles creates a large ice ball allowing for target tissue engulfment with adequate margins.
 

Liquid Nitrogen Cryoablation >

*Table 2.2 Temperature of some commonly used cryogens. Ed. Pasquali (2015). Cryosurgery: A Practical Manual. Springer 

Testimonials

“I have been using the ProSense Cryoablation System for all my cryoablation procedures for the past year. I have plenty of experience using the typical argon-based systems – and IceCure offers several advantages over those systems. First, the rate of freeze is much faster. We know from studies this is important to enhance the anti-cancer immune response from cryoablation. Second, the cost per procedure is less, not only because you can achieve larger ablation zones with a single needle, but also because liquid nitrogen is less expensive than gases needed for the other systems.”

Jason R. Williams, MD
Director of Interventional Oncology, Williams Cancer Institute,
Atlanta, GA and Mexico City, Mexico

Choose Ease of Use and Safety

As liquid nitrogen can be conveniently stored in low-pressure Dewars, the ProSense Cryoablation System requires no gas lines, no onsite technicians or specific safety rooms required to store large and hazardous high-pressure cylinder tanks required for argon-based cryoablation devices.  Liquid nitrogen is also highly available and affordable with no country-specific supply restrictions or cost risk associated with argon gas.

ProSense >

Cryoablation with the Prosense system

Step 1

The cryoprobe is inserted into the tumor at a small incision site

system_step-2

Step 2

The tumor is surrounded by an ice ball. The extreme cold kills the tumor tissue

system_step-3

Step 3

The cryoprobe is removed and a Steri-Strip is applied, requiring no stitches.

Resources

Webinars

Webinar: Cryoablation in the Thoracic Cavity

This webinar lead by Dr. Julien Frandon of the Department of Radiology at CHU de Nîmes discusses various cases performed with the ProSense™ Liquid Nitrogen (LN2) Based Cryoablation System in the thoracic cavity (i.e. lung, mediastinum). (60 minutes)

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Publications

Feasibility and Safety of Single-Probe Cryoablation with Liquid Nitrogen: An Initial Experience in 24 Various Tumor Lesions

The aim of this retrospective study was to assess the feasibility of the IceCure’s single-probe liquid nitrogen system for tumor lesions of various sizes and locations, and to evaluate the safety of cryoablation with this technique.

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Publications

Cryoablation Using Liquid Nitrogen for Metastatic Lung Cancers

This retrospective observational study conducted by Professor Hiroaki Nomori, MD found that cryoablation using liquid nitrogen would be one of the treatment methods for metastatic lung cancers <2.2 cm; and pulmonary function decreased significantly when cryoablation was performed for an

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