Cryoablation for Palliative Care

Choose to Improve Quality of Life

At IceCure, we deeply believe that every patient deserves the utmost compassion and the highest quality of life when battling benign or malignant tumors. Our ProSense Cryoablation System empowers a minimally invasive choice of treatment to help mitigate the pain often associated with metastatic or difficult to reach tumors in the body.

It’s Your Choice.

Palliative Care

Cryoablation for Palliative Care

Choose to Improve Quality of Life

At IceCure, we deeply believe that every patient deserves the utmost compassion and the highest quality of life when battling benign or malignant tumors. Our ProSense Cryoablation System empowers a minimally invasive choice of treatment to help mitigate the pain often associated with metastatic or difficult to reach tumors in the body.

It’s Your Choice.

Choose Results

A systematic review on the use of cryoablation to control cancer pain from 22 articles involving 496 patients with 580 treated lesions (including lung cancer and bone metastases) found1:

80.9%

Reduction in mean pain scores at 6 months1

59.6%

Improvement in quality of life associated with cryoablation at 8 weeks1

61.7%

Reduction in the need for
opioids at 3 months1

1Ferrer-Mileo, L., Luque Blanco, A. I., & González-Barboteo, J. (2018). Efficacy of Cryoablation to Control Cancer Pain: A Systematic Review. Pain Practice, 18(7), E69-E77. doi:10.1111/papr.12707

Testimonials

“I have been using cryoblation from IceCure for the last two years for treating patients with bone* metastatic disease… Usually the patient does not feel any pain during the treatment or afterwards.  With IceCure, we can really check the ablation area and the bouldering of the lesions because the iceball can be easily seen by using ultrasound and CT. This means we can be very safe in treating lesions without harming any sensitive structures close to the target. The results are very good and the technique is very easy.”

Franco Orsi, MD
Director Interventional Oncology
European Institute of Oncology‭, ‬Milan

*IceCure has regulatory approvals worldwide and clinical indications may vary by region. Please contact us for additional information.

Choose to Advance Palliative Care

With minimal pain, scarring and a faster recovery, minimally invasive cryoablation offers an advanced treatment experience1,2,3,4,5,6:

  • Rapid recovery: Offers lower morbidity and faster recovery than surgery and a shorter hospital stay than radiation treatment
  • Reduces the use of pain medication, including opioids (with high addictive risks), and associated side effects
  • Minimal pain and discomfort: Only a small incision is made for the needle-like cryoprobe and the cooling from the cryoablation itself reduces pain
  • Visibility of the ice-ball boundary allows ablations of close-to-nerve lesions:
    Enables targeted iceball coverage without harming any sensitive structures
  • Can be performed under light sedation: Eliminates risks from general anesthesia required during surgery

1Ferrer-Mileo, L., Luque Blanco, A. I., & González-Barboteo, J. (2018). Efficacy of Cryoablation to Control Cancer Pain: A Systematic Review. Pain Practice, 18(7), E69-E77. doi:10.1111/papr.12707

2Tuncali, K., Morrison, P. R., Winalski, C. S., Carrino, J. A., & et al. (2007). MRI-guided percutaneous cryotherapy for soft-tissue and bone metastases: Initial experience. American Journal of Roentgenology, 189, 232-239. doi:10.2214/AJR.06.0588

3Tomasian, A., Wallace, A., Northrup, B., Hillen, T. J., & Jennings, J. W. (2016). Spine cryoablation: Pain palliation and local tumor control for vertebral metastases. AJNR. American Journal of Neuroradiology, 37(1), 189-195. doi:10.3174/ajnr.A4521

4Callstrom, M. R., Dupuy, D. E., Solomon, S. B., Beres, R. A., Littrup, P. J., Davis, K. W., Paz-Fumagalli, R., Hoffman, C., Atwell, T. D., Charboneau, J. W., Schmit, G. D., Goetz, M. P., Rubin, J., Brown, K. J., Novotny, P. J., & Sloan, J. A. (2013). Percutaneous image-guided cryoablation of painful metastases involving bone: Multicenter trial. Cancer, 119(5), 1033-1041. doi:10.1002/cncr.27793

5Thacker, P. G., Callstrom, M. R., Curry, T. B., Mandrekar, J. N., Atwell, T. D., Goetz, M. P., & Rubin, J. (2011). Palliation of painful metastatic disease involving bone with imaging-guided treatment: Comparison of patients’ immediate response to radiofrequency ablation and cryoablation. AJR. American Journal of Roentgenology, 197(2), 510-515. doi:10.2214/AJR.10.6029

6Rose PS. & Morris JM. Cryosurgery/cryoablation in musculoskeletal neoplasms: history and state of the art. Curr Rev Musculoskelet Med. 2015 Dec;8(4):353-60

Choose Ease of Use and Efficiency

ProSense provides a fast and convenient minimally invasive option for palliative care of metastatic tumors: 

Workd With

Works with

existing chemotherapy, radiation, or immunotherapy, and can be combined with stabilisation, fixation and reconstruction techniques, as well as cementoplasty  

Fast and easy procedure

Cryoablation procedure takes about 1 hour from start to finish helping save physicians time and reduce waiting times

Repeatable procedure

Repeatable procedure

Allows for further treatment of metastatic tumors

Easy to Use

Efficient and user-friendly

Liquid nitrogen freezing system eliminates gas line restrictions, user-friendly touch screen system and a unique single cryoprobe design helps save time and costs. 

Choose Cryoablation for Palliative Care 

Cryoablation for palliative care of tumors is a minimally invasive procedure. Using image guidance like ultrasound or computed tomography (CT), a small cryoprobe is guided into the tumor and, extremely low temperatures are generated to turn the tumor into an ice-ball. A freeze-thaw-freeze cycle rapidly destroys the targeted tissue and leaves adjacent healthy tissue undamaged. The necrotic debris is eventually absorbed by the body. 

Resources

Webinars

Webinar: Cryoablation in the Thoracic Cavity

This webinar lead by Dr. Julien Frandon of the Department of Radiology at CHU de Nîmes discusses various cases performed with the ProSense™ Liquid Nitrogen (LN2) Based Cryoablation System in the thoracic cavity (i.e. lung, mediastinum). (60 minutes)

Read More >

Publications

Feasibility and Safety of Single-Probe Cryoablation with Liquid Nitrogen: An Initial Experience in 24 Various Tumor Lesions

The aim of this retrospective study was to assess the feasibility of the IceCure’s single-probe liquid nitrogen system for tumor lesions of various sizes and locations, and to evaluate the safety of cryoablation with this technique.

Read More >

Publications

Cryoablation Using Liquid Nitrogen for Metastatic Lung Cancers

This retrospective observational study conducted by Professor Hiroaki Nomori, MD found that cryoablation using liquid nitrogen would be one of the treatment methods for metastatic lung cancers <2.2 cm; and pulmonary function decreased significantly when cryoablation was performed for an

Read More >